Ro 60-0175 fumarate

Research use only, not for human use.

Ro 60-0175 is a potent, selective 5-HT2C receptor agonist.

Ro 60-0175 is a potent, selective 5-HT2C receptor agonist with pKi of 9, 7.5, 5.4, 5.2 and 5.6 for human 5-HT2C, 2A, 1A, 6 and 7 receptors respectively; induces hypolocomotion in rats at doses greater than 0.5 mg/kg s.c.; (0.3 and 1 mg/kg s.c.) simultaneously reduces both unpunished and punished lever pressing, a profile consistent with sedation, induces sedative-like responses via 5-HT(2C) receptor activation in vivo.

Ro 600175 fumarate

Endocrinology/Hormones

5-HT Receptor

5-HT Receptor

Neurological Disease

——

169675-09-6

342.75

C15H16ClFN2O4

>98% (HPLC)

——

C[C@@H](CN1C=CC2=CC(=C(C=C21)Cl)F)N.C(=C/C(=O)O)\C(=O)O

(S)-1-(6-chloro-5-fluoro-1H-indol-1-yl)propan-2-amine fumarate

(-20℃)

With Ice Pack

≥ 2 years